Alisma Decoction on Blood Pressure in Rats.docVIP

 PAGE \* MERGEFORMAT 9 Alisma Decoction on Blood Pressure in Rats Of: Gu Shi Jian, Wu Juan, Liu winter months, Liu Ping, Fang Nianbo, I still work [Abstract] Objective Alisma Decoction on blood pressure and normal mice. Methods awake mice using indirect manometry tail artery were measured Alisma soup , , , 4 dose group were different time points after injection of blood pressure and heart rate. Results Alisma soup , , 3 dose groups (dose volume of the order of 90,180,360 mg / kg in mice on normal blood pressure and antihypertensive effect was significant (P lt;0. 05). Alisma soup between antihypertensive effect and the dose administered 10 min and 30 min, showing a good dose-effect relationship. Alisma also observed Tom dose (360 mg dose volume / kg has a certain role in slowing heart rate. Conclusion Alisma Decoction on antihypertensive effect in normotensive mice, and a certain drug dose-effect relationship, but also has some role in slowing the heart rate. The results of further research for future Alisma Evaluation of antihypertensive efficacy and Tom laid the foundation for the mechanism. [Keywords:] Alisma soup experimental study of blood pressure dose-effect relationship Abstract: ObjectiveTo study the effect of Zexie decoction on blood pressure in mice. MethodsThe blood pressure of mice at different time points was measured after treatment with Zexie decoction of four concentrations by using the tail cuff method with a BP meter.ResultsThe results showed that Zexie decoction reduced the systolic blood pressure (SBP) in mice at a single dosage of 90 mg / kg body weight, 180 mg / kg body weight or 360 mg / kg body weight.There was a dose-effect relationship between the antihypertensive effects in four doses at 10 minutes and 30 minutes. The result also showed that Zexie decoction at the dosage of 360 mg / kg body weight had the obvious effect of reducing heart rate in mice at 10 min. ConclusionZexie decoction has the antihypertensive effect