All parties a solution to the climacteric depression central monoamine neurotransmitters in rat and reproductive endocrine effects of.docVIP

 PAGE \* MERGEFORMAT 10 All parties a solution to the climacteric depression central monoamine neurotransmitters in rat and reproductive endocrine effects of [Abstract] Objective: To study the one-Fang Xie rat model of menopausal depression monoamine neurotransmitters and reproductive endocrine intervention, and explore its mechanism. Methods: Wistar female rats were 35 were randomly divided into sham-operated group, model group, traditional Chinese medicine group, western medicine group, using ovariectomy and long-term chronic unpredictable stress the Combination of the establishment of animal model of menopausal depression. Chinese Medicine for a solution of co-parties, western medicine group to estradiol benzoate and Prozac. Measured behavioral score, sugar consumption, 24 h food intake, neurotransmitter (5  HT, 5  HIAA) and reproductive endocrine hormone (GnRH, E2, FSH, LH) levels, compared the changes in group 4. Results: Compared with model group, the Chinese Medicines Board of the behavioral score, sugar consumption and 24 h feeding volume increased significantly, endocrine hormones E2, FSH, LH, GnRH significantly improved the disorder, while the hypothalamus 5  HT, 5  HIAA were significantly higher (P amp;lt;0.05). Conclusion: The combined side is a solution of menopausal depression through the effective regulation of rat endocrine hormone levels, thus increasing the hypothalamus monoamine neurotransmitters 5  HT, 5  HIAA without achieving therapeutic purposes. [Keywords:] menopausal depression; monoamine neurotransmitter; reproductive endocrine; a solution together party; rat Menopause is the first incidence of depression in menopause, to depression, anxiety, tension as the main symptom syndrome, its incidence rate approximately 5.8% of menopausal population [1], accounting for 78% of menopausal syndrome [2]. With the gradual aging of the world’s population, female literacy knowledge and the improvement of social activities increased, th