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Atropine and pralidoxime on the efficacy of rabbit trichlorfon poisoning
Of: Han Wei Lu Qiong Pu Yanchun Li Yin
[Abstract] Objective To investigate the effects of atropine and pralidoxime trichlorfon poisoning rabbit rescue effect. Methods 10 rabbits were randomly divided into two groups of the five observed groups using trichlorfon ear vein injection of 5% solution control group, intraperitoneal injection of 5% trichlorfon solution, two rabbits were copied into trichlorfon poisoning model, save the observation group were injected with atropine, pralidoxime iodide injected with the control group were rescued, rescue medication were observed on The role of rabbits. Results After injection of trichlorfon solution, rabbits were there muscarinic symptoms, nicotine-like symptoms and central nervous system symptoms, symptoms of poisoning of the time the symptoms did not differ except miosis outside (Pgt; 0.05, The other three symptoms, such as saliva outflow, incontinence and skeletal muscle tremor were there differences in the time (all P lt;0.05. observed rabbits appear muscarinic poisoning symptoms and some symptoms of central nervous system be rescued, the control group rabbits symptoms appear nicotinic be rescued. Conclusions moderate, and severe treatment of trichlorfon poisoning, M receptor blocker (atropine and cholinesterase resurrection drug (pralidoxime iodide, Applications should be compatible with each other and learn from each other to get good results.
[Keywords:] atropine, pralidoxime trichlorfon poisoning in rabbits Trichlorfon widely used to control agriculture, forestry, gardening, pests, parasites and mosquitoes, and other livestock, as a white crystalline solid, soluble in water. As widely used in agriculture, so in use, can produce poisoning, in recent years, organic pesticide poisoning from the improper operation of protection, wrongly, be extended to individual behavior suicide schools, factories, hotels a
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