Children with pneumonia complicated by systemic inflammatory response syndrome Determination of serum TNF-a.docVIP

 PAGE \* MERGEFORMAT 5 Children with pneumonia complicated by systemic inflammatory response syndrome Determination of serum TNF-a [Abstract] Objective To investigate in children with pneumonia complicated by systemic inflammatory response (SIRS) changes when the TNF-a. Method over the same period 20 patients hospitalized with pneumonia and 25 cases of simple pneumonia and SIRS patients were measured plasma TNF-a. Results pneumonia SIRS group of TNF-a levels higher than those of pneumonia group. Conclusions TNF-a in children with pneumonia caused by SIRS. [Keywords:] pneumonia and systemic inflammatory response TNF-a SIRS refers to the body in a variety of serious infections, trauma, burns, hypoxia and reperfusion injury and other infectious and noninfectious factors stimulation produced a loss of control of systemic inflammatory response collectively. A serious infection of a bacterial toxin activation of mononuclear giant macrophages and other inflammatory cells release large amounts of inflammatory mediators and cellular toxins such as TNF-a, IL-1, and these in the body rise to a “waterfall effect” like a chain reaction, causing tissue damage. [1] TNF-a is an important inflammatory mediators, this article on the merger of pneumonia in children with SIRS blood TNF-a levels were determined. Subjects and methods 1. Study (1) pneumonia associated with SIRS group 2004.5-2004.7 children in my hospital, aged 14 days -6 months, including 11 males and 9 females, a total of 20 cases. Diagnostic criteria according to the second session of the 1996 World Pediatrics Assembly HAYDEN proposed diagnostic criteria for SIRS in children [2]. (2) election year alone hospitalized pneumonia group, the pneumonia is not consolidated as control SIRS. Including 13 males and 12 females, a total of 25 cases. The average age group and gender composition of SIRS group with pneumonia was no significant difference . 2. Research Methods (1) in