Clinical analysis of 33 cases of senile rheumatic fever.docVIP

 PAGE \* MERGEFORMAT 6 Clinical analysis of 33 cases of senile rheumatic fever Study: Lv Yingchun Chen Lin Jiang Guoping Xu Mei Han a multi Impetus Shu ZHAO Yu-Fen Chang products [Keywords:] rheumatic fever; anti-”O”; C-reactive protein Rheumatic fever (RF) is a group from the A beta hemolytic streptococcus (Group A streptococcus, GAS) throat infection induced autoimmune disease, can have systemic connective tissue disease, in particular violations of good joints, heart, skin , even can affect the nervous system, blood vessels, serosa and lung, kidney and other organs. the long-term, recurrent meningitis can lead to chronic rheumatic heart valve heart valve damage, the formation of rheumatic heart disease (RHD). With the application of antibiotics, GAS upper respiratory tract infection caused by the timely treatment and control, although significant decline in the incidence of RF, but the clinic is still rare. This retrospective analysis of clinical data of elderly patients with RF, for therapy. 1 Data and methods 1.1 Clinical data in our hospital from 2005 to 2008 were admitted to hospital 33 patients with RF, with reference to the Chinese Medical Association diagnostic criteria for rheumatic fever diagnosis and treatment of rheumatism branch Guide (draft) (1). The patients were divided into old age group and the non-elderly group. Old 10 patients, aged 64 to 90 (mean 77.7) years old, 3 males and 7 females. non-elderly group of 23 patients aged 11 to 54 (mean 27.5) years, 10 males and 13 females. 1.2 observed in patients with general information on project record, clinical manifestations, associated diseases, laboratory indicators. 1.3 Laboratory tests were done in all patients routine blood test, erythrocyte sedimentation rate, C-reactive protein (CRP), anti-”O”, anti-CCP antibodies, antinuclear antibodies, IgA, IgG, IgM, complement C3, C4 test, both groups were 3 Bone marrow smear examination. old age group, 4 cases, 9 cases of non-elder