Clover yellow mixture on immune function in mice Experimental Study on Effects.docVIP

 PAGE \* MERGEFORMAT 17 Clover yellow mixture on immune function in mice Experimental Study on Effects Author: Yun Chen-Xia Yu Xiaoling Wu Guang Xiao Jian Wei Haihong Xiao Yanfen Huang Yan Wang Kun [Abstract] Objective To investigate the clover yellow mixture of normal mice and mice immunosuppressed immune function. Methods clover yellow mixture to the normal mice and cyclophosphamide (CTX) immunosuppressed mice fed, and then weighing to detect thymus, spleen weight, with the neutral red colorimetric assay of macrophage activity, by RIA assay interleukin -2 (IL-2) content, using MTT assay NK cell activity and T lymphocyte proliferation. Results clover yellow mixture of normal mouse thymus, spleen weight and cellular immune function had no significant impact on the CTX significantly inhibit the immune resistance to the role of the immune-suppressed mice can increase the weight of thymus and spleen, enhance macrophage phagocytic role in promoting IL-2 secretion, increase NK cell activity and T lymphocyte proliferation. Conclusion clover yellow mixture on cellular immune function in normal mice had no significant effect, but resistant to CTX cellular immune function in mice in vivo. [Keywords:] Clover yellow mixture of macrophage interleukin -2 T lymphocyte NK cell Clover yellow mixture is based on the basic theory of traditional Chinese medicine and prescriptions set of square principle put forward by the treatment of hepatitis B virus infection-based self-made side (Chinese-medicine scientists, led by Professor Deng Jiagang expert groups to develop), by three sisters, Phyllanthus beads, Gynostemma, Astragalus, Atractylodes, Chinese herbal medicine made Tianqi, etc., there are detoxification, Lishi stasis, Qi spleen, righting Hugan achievements. In vitro studies have shown that clover yellow mixture on the 2215-cell secretion of HBsAg and HBeAg all have a certain degree of inhibition [1]. In order to explore its normal or immunosuppressed mice whether the reg