Conventional radiotherapy in patients with nasopharyngeal carcinoma after radical survival analysis of 335 cases.docVIP

 PAGE \* MERGEFORMAT 18 Conventional radiotherapy in patients with nasopharyngeal carcinoma after radical survival analysis of 335 cases Of: Cai Chuan-shu, Zhang Wei Jian, Xiu-Ying Chen, Jun-Wei Chen, Feng Liu, Hong-jin Province [Abstract] Objective To summarize the conventional radiotherapy of nasopharyngeal carcinoma patients after radical long-term survival. Methods of pathologically confirmed nasopharyngeal carcinoma, a continuous line of conventional radical radiotherapy in patients with newly diagnosed 335 cases of male to female ratio was 2.28:1, the incidence of the median age of 47 years (15 to 77 years old, , , , a and b are respectively 3.9%, 19.4%, 35.2%, 40.0% and 1.5%. linear accelerator, low melting point lead block, conventional fractionated external beam, nose pharyngeal primary tumors, median dose 72 Gy, each 1.8 ~ 2.0 Gy, face, neck face, neck joint field + field + ear before the United contraction phase of exposure to wild three-.57.0% of patients received cisplatin + fluorouracil 1 to 2 cycles of induction chemotherapy and / or 1 to 5 cycles of adjuvant chemotherapy. The results follow-up rate of 92.1%, with a median follow-up time of 55 months (1 to 104 months. The overall 5-year overall survival, progression-free survival, recurrence-free survival, distant transfer of survival, progression-free rate, the regional control rate and distant metastasis rates were 71.4%, 61.3%, 66.2%, 65.9%, 70.2%, 86.6% and 79.6%, , , , a and b of 5-year patient survival rates were 100.0%, 86.2%, 75.7%, 57.4% and 7.0%. the higher incidence of late damage were xerostomia, neck fibrosis, trismus, hearing loss, dental caries and tooth loss, dysphagia, voice changes. radiation encephalopathy, brain damage after an independent group factors were primary tumor dose (P = 0.032, T stage (P = 0.015. Conclusion large dose of the primary tumor, T min should pay attention to prevention and treatment of late radiation encephalopathy. [Keywords:] neoplasms, su