Cyathula decoction of spontaneously hypertensive rats blood pressure and left ventricular hypertrophy in.docVIP

 PAGE \* MERGEFORMAT 5 Cyathula decoction of spontaneously hypertensive rats blood pressure and left ventricular hypertrophy in [Abstract] Objective: To observe the Cha Chuan Achyranthes Decoction on spontaneously hypertensive rats (SHR) blood pressure and left ventricular hypertrophy (LVH) effects. Methods: SHR group fed with different doses of Cyathula decoction 8 weeks, and to enalapril as the control drug, in order to SHR fed with drinking water as the blank control group and watch Cha Chuan Achyranthes Decoction descending pressure effects, were sacrificed after 8 weeks, take left ventricular muscle weighing, calculating the ratio of left ventricle and body weight to measure the heart of Cyathula decoction protection. Conclusion: There Cyathula SHR blood pressure lowering effect and can improve and treatment of left ventricular hypertrophy in SHR. [Keywords:] Cyathula; spontaneously hypertensive rats; blood pressure; left ventricular hypertrophy Amaranthaceae Achyranthes for the perennial herb Achyranthes root dry. Modern pharmacological studies have also confirmed that single herb Achyranthes have a certain role in lowering blood pressure. This paper studies the role of Achyranthes bidentata on blood pressure regulation and its mechanism of action, provide reference for clinical medicine. 1 Materials and methods 1.1 Drugs Cyathula decoction: Cyathula purchased from Jilin Province Chinese Medicine Hospital, plus amount of boiling distilled water three times, the merger filtered liquid, concentrated into a 1g crude drug / mL of the liquid, sealing, high pressure sterilization, refrigerator storage backup. 1.2 Experimental animals and grouping Selected spontaneously hypertensive rats (SHR) 50 pieces by the Chinese Academy of Medical Sciences Institute of Laboratory Animal, male, 14 weeks old, were randomly divided into 5 groups, SHR control group, daily fed with drinking water; Cyathula decoction of high, medium and low-dose group, the daily gavage C