Cystatin C on the early diagnosis of diabetic nephropathy.docVIP

 PAGE \* MERGEFORMAT 7 Cystatin C on the early diagnosis of diabetic nephropathy [Abstract] Objective evaluation of serum cystatin C (Cystatin C in the diagnosis of diabetic nephropathy. Methods 78 patients with diabetes by albumin excretion rate (UAER divided into 3 groups, normal albuminuria group (Ⅰ group) 21 patients, microalbuminuria group (Ⅱ) were 30 and massive proteinuria group (Ⅲ group) 27 cases, the control group (those who pass the physical examination). measured in each group Cystatin C, serum creatinine (Scr, creatinine clearance ( Ccr. Then on the indices were compared using statistical software SPSS11.0 analysis and correlation analysis. results in diabetic patients measured by the average value of Cystatin C higher (P lt;0.05, and serum creatinine in group Ⅰ and Ⅱ the average of the measurements no significant difference in Cystatin C and the correlation with Ccr Scr and Ccr than a good relationship. Conclusion Cystatin C blood of diabetic nephropathy in type 2 early diagnosis is more sensitive than serum creatinine. [Keywords:] cystatin C creatinine creatinine clearance rate of diabetic nephropathy Diabetic nephropathy (DN) in diabetic (DM) is one common and serious complications. Currently detection of microalbuminuria in early diabetic nephropathy is the main diagnostic methods, but are vulnerable to heat, heart failure, urinary tract infection, high blood sugar and other factors. In recent years, studies [1] suggest that cysteine #8203;#8203;inhibit the enzyme C (Cystatin C GFR reliable for the detection of new indicators, and regardless of age, gender impact, in children, the elderly, middle-aged in both applied and therefore We were determined Cystatin C and Scr to explore their value in early diagnosis of DM. 1 Materials and methods 1.1 Clinical data for the medical control group, those who pass the 57 patients, 37 males and 20 females, aged 27 to 75 years, mean age (49.2 + -12.5 years old .78 cases were selected