Danshen injection on the rabbit epicardial ventricular arrhythmia action potential of single-phase.docVIP

 PAGE \* MERGEFORMAT 12 Danshen injection on the rabbit epicardial ventricular arrhythmia action potential of single-phase Of: Xiao Ye-Wei, He Guangfeng, Liu purple full, Liu Xixiu, Mr Fung, plate Qiang [Abstract] Objective Danshen injection on ventricular arrhythmias in rabbit epicardial monophasic action potential (MAP changes, try to reveal its role in myocardial ischemia due to arrhythmia mechanism. Methods 20 rabbits were randomly divided the control group and the SM group, in the context of myocardial ischemia and arrhythmia were recorded before and after the detection of the observed indicators for the control and the groups were compared before and after. Results In the control group and the SM group in the arrhythmia, the mean heart rate, MAP amplitude (MAPA, the maximum rate of increase, were higher than their post-arrhythmia (P lt;0.05), the control group and the SM group were lower than in the arrhythmia before the MAPD90 after their arrhythmia (P lt;0.05), arrhythmia before and after the control group and SM group, the index P lt;0.05, with statistical significance. Conclusion SM can improve myocardial tolerance to ischemia and the ability to play the ATP-sensitive potassium channel opener effect, which may be protective effect of Danshen on myocardial ischemia with enhanced the basis of electrophysiological effects. [Keywords:] Salvia, ventricular arrhythmias, epicardial monophasic action potential Department of perennial herb Salvia Salvia miltiorrhiza Labiatae dry root of Salvia miltiorrhiza extracts of Salvia modern medical research confirmed that with the expansion of the coronary arteries, increasing blood flow, improving myocardial ischemia and improve myocardial contractility, increased cardiac output accelerate the cardiac repair, myocardial injury protection. In recent years some studies suggest that SM and improve the anti-arrhythmic effects of myocardial ischemia with a more significant role. In this study, Professor Feng Zh