Dendrobium experimental chronic atrophic gastritis Yu Yan mechanism_0.docVIP

 PAGE \* MERGEFORMAT 11 Dendrobium experimental chronic atrophic gastritis Yu Yan mechanism Of: Lu Gaoxiang, Pan Xiao-yan, Pan Xingshou, Li talent, Vivaldi [Abstract] Objective Dendrobium chronic atrophic gastritis (CAG) of the control mechanism, to provide experimental basis for clinical. Methods ammonia, ethanol and sodium deoxycholate gavage method, made #8203;#8203;of CAG rat model. After the model Dendrobium decoction treated group treated for 5 weeks, and CAG gastric mucosal blood flow and prostaglandin E2 (PGE2 changes. and with the model group and control group. the treatment group and model group after modeling (before treatment the gastric mucosal blood flow and PGE2 levels were lower than control (P all lt;0.01. the treatment group 5 weeks after treatment by the dendrobium, the gastric mucosal blood flow than the model group (P lt;0.01), compared with the control group, no significant difference (Pgt; 0.05), PGE2 content in the treatment group compared with model group (P lt;0.01), compared with the control group, no significant difference (Pgt; 0.05). Conclusion Dendrobium CAG in rats can improve gastric mucosal blood flow, increase their PGE2 content suggests the gastric mucosa of rats with CAG improve its barrier function and the role of Yu-yan, a preventive effect on the CAG. [Keywords:] animal experiments, rats, Dendrobium, gastritis, atrophic, gastric mucosal blood flow, prostaglandin E2 Abstract: Objective To investigate the anti-inflammatory mechanism of dendrobium decoction on models of experimental chronic atrophic gastritis (CAG) in rats and to provide laboratory evidences for clinical use of dendrobium decoction. Methods The CAG models in rats were produced by intragastric ammonia water, ethanol and deoxysodium cholate infusion. The model rats were given dendrobium decoction for five weeks. The measurement of gastric mucosa blood flow volume and prostaglandin E2 (PGE2) was conducted and a comparison of these two indices among