Detection of tumor markers in Gastric Cancer Research.docVIP

 PAGE \* MERGEFORMAT 12 Detection of tumor markers in Gastric Cancer Research [Keywords:] Progress in gastric cancer tumor markers Gastric cancer is a serious threat to human diseases, the mortality rate of cancer mortality in the world’s No. 2. On a scientific and effective implementation of the incidence of gastric cancer, prevention, implementation of the gastric cancer screening, early diagnosis and early treatment is to reduce the incidence of gastric cancer and mortality in the most effective strategy. now rely mainly on endoscopic diagnosis of gastric cancer, pathology, X ray and other technologies have three check-invasive means, to bring some patients with physical and mental damage. to find a simple, fast, no damage , no pain screening method, in recent years, serum or other body fluids by detecting the tumor marker, according to their qualitative or quantitative changes, may aid cancer treatment. An overview of tumor markers Tumor Markers (Tumor markers, TM) is that the tumor is present and reflect the biological properties of certain chemical substances. Back in 1846, Bence Jones first found in the urine and detect specific proteins in multiple myeloma (a type of immune myosin light chain). to the early twentieth century, scholars have successively raised hormone and tumor-related ectopic adrenocorticotropic hormone (ACTH), human chorionic gonadotropin (HCG) and so on, then, in 1933 and have been discovered in 1959 with prostate cancer related to prostatic acid phosphatase (PAP) isoenzymes and tissue differentiation of enzymes. All these results can be seen as the first phase of TM of the Soviet scholars Abelev .1963 primary liver cancer found landmark AFP (AFP), 1965 Gold and Freedman in Canada scholars discovered another important cancer marker carcinoembryonic antigen (CEA), AFP and CEA research finding is that the second phase of TM [1] . Since then, TM concept was the product of the secretion of tumor cells linked Kobler and Milstei