Determination on the compound Yimu Ferulic Acid Capsules.docVIP

 PAGE \* MERGEFORMAT 12 Determination on the compound Yimu Ferulic Acid Capsules Of: Qi Zhang Guomin Yeung Chi Hung Chang Li Zhijun [Abstract]: Objective compound Yimu Determination of ferulic acid capsule method. Methods ZORBAXSB-C18 column, mobile phase of acetonitrile -0.2% phosphoric acid (12 ︰ 88), detection wavelength 316 nm, flow rate 1.0 mL / min. Results of ferulic acid in the 0.8 ~ 13 μg / mL range was a good linear relationship (r = 0.999 99, n = 6), the average recovery was 103.0% (RSD = 0.4 %, n = 5). Conclusion The method is simple and feasible, accurate, reproducible, high recovery rate can effectively control the quality of compound Yimu capsules. [Keywords:] ferulic acid compound Yimu high performance liquid chromatography capsule Abstract: Objective To estblish a HPLC method for content determination of ferulic acid in compound prescribe Motherwort Herb capusle. Method The column ZORBAXSB-C18 was used with Acetonitrile-0.2% phosphoric acid aqueous solution (12:88) as mobile phase, and detective wavelength was 274 nm, the flow rate was 1.0 mL / min. Result Within the range of 0.8 ~ 13 μg, ferulic acid presented a fine linear relationship (r = 0.999 99, n = 6). The average recovery was 103.0% (RSD = 0.4%, n = 5). Conclusion The method is suitable, accuracy is high and reproducibility is good, recovery is high, and can control the quality of compound prescribe Motherwort Herb capusle. Keywords:: compound prescribe Motherwort Herb capsule, ferulic acid, HPLC Capsule is the original Yimu Compound Yimu granules (WS3-B-1812-94) improved dosage forms, from Motherwort, Angelica, Chuanxiong, woody herb component 4, with blood circulation to regulate menstruation, analgesic effect of qi, qi stagnation for Blood, irregular menstruation, dysmenorrhea, postpartum abdominal pain, the treatment of blood stasis. collection is contained in lt;lt;Republic of China Ministry of Health, Drug Standardsgt;gt; [1], in which no determination method. T