Early normalization of severe pain in patients with multiple trauma stress response.docVIP

 PAGE \* MERGEFORMAT 11 Early normalization of severe pain in patients with multiple trauma stress response OF: Ming-Hua Liu, Wen-liang, Yinchang Lin, Qu Jifu, Juan [Abstract] Objective To investigate the standardization of pain in patients with severe multiple trauma patients the impact of traumatic stress. Methods 50 patients with severe multiple trauma patients were randomly divided into two groups with fentanyl PCA (patient controlled analgesia and traditional pain management group, the injured within 3 hours after the pain started in the hospital immediately, and 24.48 hours serum cortisol, tumor necrosis factor-@ (TNF @, interleukin 6 (IL 6 level, comparative analysis of the differences. Results There were no baseline significant difference in the first 24.48 hours, fentanyl PCA group cortisol, TNF @, IL 6 levels were significantly lower than traditional pain management group (P lt;0.05). Conclusion Compared with traditional pain management, early treatment of standardized pain can significantly reduce post-traumatic stress reactions. [Keywords:] multiple trauma, pain, stress response Abstract: Objective To evaluate the influence of early analgesia by fentanyl on stress response of multiple trauma patients.Methods Fifty cases with severe multiple trauma were randomly divided into 2 groups: fentanyl PCA group and traditional treatment group.Analgesia was performed within 3 hours after injury , and the blood samples were obtained to determine the serum level of cortisol, TNF @, IL 6 at 0,24,48 hours after admission.ResultsThe primary level of each item had no significant difference between 2 groups.The levels of cortisol, TNF @ and IL 6 at 24 and 48 hours in fentanyl PCA group were lower than those in traditional treatment group (P lt;0.05). Conclusion Compared with traditional treatment group, early analgesia by fentanyl could repress the post traumatic stress reaction. Keywords:: multiple trauma; analgesia; stress response Traumatic stre