Early Parkinsons Bingti evoked potential components of high frequency oscillations observed.docVIP

 PAGE \* MERGEFORMAT 11 Early Parkinson’s Bingti evoked potential components of high frequency oscillations observed Author: Huang Chun-Hui Chen goods vehicles root LIU Chang-yun ZHENG Sheng Zhuang Xiaoyun Fang Jiang [Abstract] Objective To investigate the somatosensory evoked potential (SLSEP) high-frequency oscillatory component (HFOs) in early Parkinson’s disease (PD) in the pathological abnormalities and its possible physiological basis. Methods 48 patients with definite diagnosis of PD patients and 40 age-matched healthy volunteers who carry out the median nerve somatosensory evoked potentials and HFOs testing, subjects were compared conventional somatosensory evoked potential components and HFOs of each index differences; comparison Conventional somatosensory evoked potential components and HFOs of the abnormal rate. Results Compared with control group, case group HFOs decrease in the number and the duration shorter HFOs between the two groups the number and duration of the differences in statistically significant, while the magnitude of difference was not statistically significant; SLSEP high-frequency abnormal oscillation component significantly abnormal rate than conventional components of a high. Conclusion In PD patients, SLSEP of HFOs may appear obvious abnormality, mainly for the number of HFOs fewer, shorter schedule, this abnormality on clinical diagnosis and study of the origin of HFOs have a certain value. [Keywords:] high-frequency oscillations of somatosensory evoked potential components of Parkinson’s disease There are many scholars at home and abroad with Parkinson’s disease (PD) for a variety of neural electrophysiological studies 〔 1,2〕 , but found no indicators of what kind of electrophysiology sensitive and early diagnosis of PD is accurate. By the results of previous studies show that early stage PD, somatosensory evoked potentials (SLSEP) before the central components of the higher rate of abnormal 〔 3〕 , a recent study suggests t