Ecdysterone cream on the wound healing and capillary density.docVIP

 PAGE \* MERGEFORMAT 16 Ecdysterone cream on the wound healing and capillary density Of: Zhenggao Yun, Wu Xu, Li Yu Long, Zhang spent [Abstract] Objective ecdysterone cream rabbit trauma model of experimental wound healing efficacy of the role, so as to promote more ecdysterone cream find evidence of the role and mechanism. Method first the fabrication of ecdysterone cream, The weight will be similar to 32 New Zealand rabbits sake of cortical defect prepared animal models of trauma, the back of each rabbit three wounds were deposited to the blank cream base, cream and Yunnanbaiyao ecdysterone Band-Aid. including 8 rabbits were 4,8,12 days after modeling shot wound healing, statistics of their size, and calculate the rate of wound healing all wounds; the other 24 rabbits were divided into 3 batches after modeling 4,8,12 days observed by micro-circulation detection and analysis system wound capillary density. the rate of wound healing results of statistical analysis showed that: ecdysterone cream significantly promote wound healing (P lt;0.01), efficacy and Yunnanbaiyao similar (Pgt; 0.05); capillary Statistical analysis showed that vascular density: wound ecdysterone cream group compared with the other two groups, the capillary density generates a larger (P lt;0.01); pathological observation: ecdysterone cream group epithelial cells, endothelial cells and fibroblasts more. Conclusion ecdysterone cream on experimental rabbit model of traumatic defects of the more significant role in promoting, promoting more use of drugs for clinical screening of a new idea. [Keywords:] ecdysterone; Yunnanbaiyao; trauma; wound healing; rabbit Abstract: Objective To research and prove the effect on promotion of wound healing of the ecdysterone cream and to find its mechanism.Methods Eight New Zealand rabbits were used as wounding animal models, each of which had 3 separated full thickness skin wounds and were treated with cream substrstum, ecdysterone cream and Yunnan