Edaravone nimodipine treatment of acute cerebral infarction.docVIP

 PAGE \* MERGEFORMAT 12 Edaravone nimodipine treatment of acute cerebral infarction [Abstract] Objective To observe edaravone nimodipine treatment of acute cerebral infarction. Methods 97 cases of acute cerebral infarction were randomly divided into two groups, control group of 46 cases with conventional treatment, 51 patients in the conventional treatment group, treatment on the plus edaravone injection 30 mg, add 100 ml normal saline infusion, 2 times / day, supplemented by intravenous and oral nimodipine treatment, two groups were 15 d to 1 course of treatment, after a course assessment of the efficacy between the two groups before treatment and after treatment in patients with neurological deficit scores and clinical efficacy. treated group neurological deficit scores compared with the control group was statistically significant (P lt;0.05), total effective rate was 86.27%, significantly higher than the 69.57% (P lt;0.05). Conclusion Edaravone is an effective treatment of acute cerebral infarction neuroprotective agents, nimodipine therapy better. [Keywords:] edaravone; nimodipine; acute cerebral infarction Acute cerebral infarction a serious threat to human health, mortality and disability is very high. The pathogenesis of complex systems from a variety of brain injury mechanisms are involved in the pathological process, currently no specific treatment. Ischemic penumbra of acute cerebral infarction neuroprotective treatment area has been a hot topic of clinical neurology. edaravone is a novel free radical scavenger, on cerebral ischemia is produced by neural cell scavenging free radical, protective effect on nerve cells to protect the brain tissue as little as possible damage by various metabolic poisons, and thus improve prognosis. We May 2007 ~ August 2009 between the 51 patients in our hospital with acute cerebral infarction and edaravone injection nimodipine treatment, achieve a satisfactory effect, the report is as follows. Materials and