EB virus latent membrane protein (LMP1) and expression of survivin in nasopharyngeal carcinoma.docVIP

 PAGE \* MERGEFORMAT 18 EB virus latent membrane protein (LMP1) and expression of survivin in nasopharyngeal carcinoma 【Abstract】 Objective To investigate the nasopharyngeal squamous cell carcinoma of EB virus latent membrane protein LMP1, and survivin expression and prognosis. Methods The immunohistochemical SP method, 83 cases of nasopharyngeal squamous cell carcinoma of the organizations LMP1 and survivin tags, analyzed the clinical stage, radiation therapy within three years after the results of relationship. The results of LMP1 expression and clinical stage (Pgt; 0.05), but relapse within three years after radiotherapy (P lt;0.05). survivin and clinical stage, relapse within three years after radiotherapy (P lt;0.05). LMP1 and survivin are associated (P lt;0.05). Conclusion LMP1 and survivin in nasopharyngeal carcinoma has important prognostic value, can be used for clinical treatment of the reference index. Keywords: nasopharyngeal carcinoma LMP1; survivin immunohistochemistry Expressions of Epstein  Barr Virus Latent Membrane Protein 1 (LMP1) and survivin in Nasopharyngeal Carcinoma and their Clinical Significance Keywords:: Nasopharyngeal; Carcinoma; LMP1; survivin; Immunohistochemical method NPC (Nasopharyngeal carcinoma, NPC) is a common malignant tumor in China, particularly Guangdong and Guangxi areas of high-fat, with the gradual in-depth on the NPC study, EBV infection and is closely related to people’s NPC has been recognized. survivin is an inhibitor of apoptosis, studies have shown that the degree of survivin expression in stage of disease progress and the extent of malignant tumor tissue is consistent. We used immunohistochemistry to detect NPC in poorly differentiated squamous cell carcinoma of the most common pathological tissues and survivin expression of LMP1, combined with clinical stage, three years after radiotherapy for recurrence of such information as to whether the study to explore both in the NPC the r