Effect of dexamethasone on side effects of epidural morphine.docVIP

 PAGE \* MERGEFORMAT 7 Effect of dexamethasone on side effects of epidural morphine [Abstract] Objective of dexamethasone to reduce or eliminate postoperative epidural analgesia produced by morphine side effects. Methods ASA Ⅰ ~ Ⅱ grade, no organic diseases, 100 patients with cesarean section, according to the town after different load formula pain were randomly divided into two groups: Ⅰ group (M group) of morphine 1 mg; Ⅱ group (MD group), morphine 1 mg + dexamethasone 5 mg, with both groups to 5 ml with a saline injection , 50 patients in each group, randomized controlled clinical study. Results Ⅰ, Ⅱ postoperative 24 h, MAP, heart rate, no significant difference. Ⅱ nausea and vomiting, pruritus, sacrococcygeal water fewer cases of herpes occur in group Ⅰ, incidence of urinary retention compared the two groups were significantly different (P lt;0.05). Conclusion Dexamethasone significantly reduced postoperative epidural analgesia morphine urinary retention, nausea, vomiting, skin itching and the occurrence of herpes sacrococcygeal water and does not affect morphine analgesia intensity and duration of analgesia. [Keywords:] dexamethasone; morphine; epidural analgesia; adverse reactions Epidural injection of morphine analgesic effect in the theory and has been fully affirmed the clinical, there are some reports of its side effects. But urinary retention, nausea, vomiting, skin itching, sacral therapy of herpes little water. This observed in patients with dexamethasone to reduce or eliminate postoperative side-effects produced by morphine. 1 Anesthesia and Analgesia 1.1 General Information Select ASA Ⅰ ~ Ⅱ grade, no organic diseases, 100 patients with cesarean section, according to the different postoperative analgesic load formula were randomly divided into two groups: Ⅰ group (M group); Ⅱ group ( MD group), 50 patients in each group. the two groups were the basic situation, the amount of anesthetic drugs and surgical time, no significant differe