Endometriosis causes stem cell theory.docVIP

 PAGE \* MERGEFORMAT 18 Endometriosis causes stem cell theory Of: Huang Yuting, Chengming Jun, Xu Jian Cong [Keywords:] stem cells, endometriosis, causes Endometriosis (endometriosis, EM is the most common benign gynecological diseases, the incidence rate of 10% to 15%, but the current treatment is not satisfactory. EM’s cause is not yet clear, the current doctrine are not fully explain the clinical incidence of various types of EM. Therefore, to further explore the etiology of EM for the diagnosis and treatment guidance and find new ways of great significance. With the deepening of stem cell research, more and more evidence EM may be related to various sources of stem cells, EM is a view of stem cell-related diseases, researchers are more and more attention. A variety of existing etiological hypothesis For EM, pathogenesis, studies have more in-depth, there is now a variety of theories, the most widely accepted theory of Sampson (the traditional doctrine of endometrial planting) that EM is a membrane with blood reflux into the abdominal cavity, ovary and adjacent planted in pelvic peritoneal surface, continue to grow, spread and form, with the formation of repeated bleeding menstrual cycle endometrial cysts. Hirata [1] using the GFP tracer ectopic endometrium in mice supported this theory, but men patients in long-term use of estrogen therapy, also can occur EM, this phenomenon can not be explained by the growing endometrium. coelomic metaplasia theory that the embryonic development, the Mullerian and ovarian surface germinal epithelium pelvic Fumo is highly chemical and biological potential from embryonic body cavity of epithelial cells from ectopic endometrial tissue is derived from the body cavity epithelial metaplasia, and pathological studies have provided evidence Weigaixueyue [2]. However, these theories are not fully explain the clinical incidence of all types of EM. The study starts to look more and more immune factors, genetic facto