Epalrestat alone treatment of diabetic peripheral neuropathy in the literature of_0.docVIP

 PAGE \* MERGEFORMAT 7 Epalrestat alone treatment of diabetic peripheral neuropathy in the literature of [Abstract] Objective To evaluate the Epalrestat treatment of diabetic peripheral neuropathy, the clinical efficacy and safety. Method to retrieve the China Journal Net (CNKI literature database containing information about Epalrestat treatment of diabetic peripheral neuropathy study, based on inclusion and exclusion standard collection of literature on effectiveness. Results efficacy evaluation were included nine clinical controlled study, efficient Epalrestat group (75.0%) than control group (44.9%). Conclusion epalrestat the treatment of diabetic peripheral neuropathy treatment is effective. [Keywords:] Epalrestat, diabetes, neuropathy Epalrestat (Epalrestat) is currently the only listed the aldose reductase inhibitor, reversibly suppressed and the pathogenesis of diabetic complications related to the polyol sorbitol metabolism of glucose into the role of aldose reductase and . This product is from Japan, Ono Pharmaceutical Development, in 1992, first listed in Japan, in 2004 the development of Yangtze River Pharmaceutical Group epalrestat in the domestic market. This product can be used for prevention, and treatment of diabetes mellitus to improve the peripheral nerve disorders ( numbness, pain, vibration, paresthesia, and cardiac anomalies (shown higher glycosylated hemoglobin values. In this study the evaluation, analysis Epalrestat study with the basis, Epalrestat alone in the treatment of diabetic neuropathy side a summary of the literature in order to better illustrate epalrestat clinical efficacy of treatment of diabetic peripheral neuropathy, clinical treatment. 1 study Between 2004 and 2009 published in the China Journal Net (CNKI the United Epalrestat treatment of diabetic peripheral neuropathy research literature. 2 Methods 2.1 The literature search with “epalrestat” as key words, find the China Journal Net (CNKI database, s