Epidural anesthesia with and without oxygen oxygen serum SOD MDA observed changes.docVIP

 PAGE \* MERGEFORMAT 6 Epidural anesthesia with and without oxygen oxygen serum SOD MDA observed changes [Abstract] Objective To observe the surface is not high epidural anesthesia, SPO2 oxygen under normal circumstances, conventional face mask on serum SOD, MDA in. Methods 36 cases of epidural anesthesia patients, ASA Ⅰ ~ Ⅱ grade, anesthesia level of not more than T6 , operative time greater than 4h, preoperative spo2gt; = 95%, were randomly divided into two groups (n = 18 cases: a conventional oxygen mask, a group of non-oxygen anesthesia in both groups before and at the end of surgery a determination of pumping blood superoxide dismutase (SOD and malondialdehyde (MDA. Results oxygen group before surgery, decreased SOD contrast, the difference was statistically significant (P lt;0.05), while the MDA and oxygen group is not MDA, SOD was no significant difference, observed in operation SPO2 case slightly higher than the non-oxygen group oxygen group, but they were within the normal range. Conclusion of anesthesia below the T6’s 4 ~ 6h of SOD surgery can cause decreased oxygen, due to changes in the design SPO2 range is small, and no changes in MDA, so the oxygen and oxygen on oxygen free radical activity is not the result of no effect. [Keywords:] epidural anesthesia, oxygen, SOD, MDA In recent years, the significance of free radicals in medicine have become an increasing emphasis on basic and clinical scholars, both in the lives of some of the activities of the body of some beneficial aspects, but also involved in the pathological damage of living organisms. Prolonged inhalation of some clinical pure oxygen, hyperbaric oxygen causes decreased SOD, MDA increased structural damage caused by tissues and cells many of the research report [1], lowering the concentration of often-reported effect of oxygen inhalation, in this study are not high epidural anesthesia level , SPO2 normal circumstances, conventional oxygen mask on serum SOD, MDA impact. 1 Subj