Estrogen and female skin aging.docVIP

 PAGE \* MERGEFORMAT 15 Estrogen and female skin aging Keywords: estrogen; skin aging; women Domestic and international studies have found that estrogen on the human body’s many systems, especially reproductive, nervous, cardiovascular and motor systems have an effect. The skin is an estrogen-sensitive organs, but, on the effects of estrogen on the skin of less 1. Estrogen molecular pathways in the skin and acting on the same other non-reproductive tissues, namely through the estrogen receptor (estrogen receptor, ER) play a physiological role. As women age, 30 years after having been declining estrogen levels, particularly low levels of estrogen after menopause accelerates the natural aging and photo aging skin, skin atrophy, skin collagen content and water content decreased, reduced skin elasticity, sebum reduced secretion, and a relatively high androgen symptoms. 40 years since the last century, the first application of systemic estrogen therapy, there has been found that estrogen is visible on the skin effects, especially anti-aging and accelerated skin wound healing in postmenopausal women. Aging is a universal law of nature, more intuitive skin aging, skin aging women, and significantly faster than men, seriously affecting their social and psychological state, this paper reviews the effect of estrogen on skin structure and function for delayed intervention in the skin of estrogen aging in particular, to improve the quality of life in postmenopausal women provide a theoretical basis. 1 Effects of estrogen on skin structure and function 1.1 Effects of estrogen on skin thickness and collagen content of skin collagen is the main visible component, the dermal collagen contains 14 species, mainly of collagen type and . The most abundant collagen type , accounting for about 80% of the total, mainly in the dermal reticular layer; collagen accounts for about 10% of the total, mainly in the dermal papilla layer and new collagen site. Skin aging