External application of Chinese medicine in treatment of age-adjusted clinical analysis of herpes zoster.docVIP

 PAGE \* MERGEFORMAT 15 External application of Chinese medicine in treatment of age-adjusted clinical analysis of herpes zoster [Abstract] Objective To observe the effect of the combination of in tune with the topical treatment of senile herpes zoster, from the perspective of evidence-based medicine assessment of its efficacy. Methods A randomized, open, positive parallel controlled trial method, met the inclusion criteria 156 patients were randomly divided into two groups and the control group (78 cases). Observation group in tune with the external application of Chinese medicine, the control group was given acyclovir, poly. Are observed 10 d is a cycle. Results The total effective observation group (98.70%) than control group (84.62%), significant difference between the 2 groups (P lt;0.05), symptoms improved observation group (only blisters, crusted , pain) than the control group (P lt;0.05), visual analog scale (VAS) integral value than the control group (P lt;0.05), the observation group the incidence of postherpetic neuralgia (2.60%) lower than the control group (39.7% ), immunoglobulin (IgM, IgG, IgA) down range than the control group (P lt;0.05), T lymphocyte subsets CD3 +, CD4 +, CD4 + / CD8 + increase rate than the control group (P lt;0.05), CD8 + down rate than the control group (P lt;0.05). Evidence-based Clinical Evaluation: OR = 6.82,95% CI = 1.60 ~ 29.089, RR = 0.17, 95% CI = 0.04 ~ 0.73, RRR = 83.0%, 95% CI = 27.0% ~ 96.0%, ARR = 12.8%, 95% CI = 4.00% ~ 13.68%, NNT = 8,95% CI = 4 ~ 25 (cases). Conclusions Treatment of Traditional Chinese Medicine External Treatment of Senile Herpes Zoster , and can be cured effectively prevent the aftermath of herpes zoster neuralgia, and may adjust the age-related immune function of patients with herpes zoster. [Keywords:] topical therapy, Chinese medicine, acyclovir, herpes zoster Abstract: Objective To observe the therapeutic effect of Chinese medicine in treating elderly herpes zoster, and study