Extraction of wood in costunolide and lactone dehydrogenase A preliminary study of factors.docVIP

 PAGE \* MERGEFORMAT 7 Extraction of wood in costunolide and lactone dehydrogenase A preliminary study of factors Of: Liu Jun Hong, Li Dihua, Wu Xiaoxian [Abstract] Objective To study the solvent, temperature and heating time on the active ingredient costunolide wood and lactone dehydrogenase. Methods ethanol extraction of water and wood, respectively, to extract the temperature control in different and the heating time range, with the HPLC method costunolide and the content of lactone dehydrogenase. Results of alcohol extract of costunolide and lactone dehydrogenase is much higher than the water content of extract, ethanol as solvent, small changes in the two ingredients, with water as solvent, with the temperature, heating time prolonged, the two components decreased significantly, especially costunolide. Conclusion solvent and temperature on the costas hydrocarbons lactones of the most significant, the time factor, followed by the preparation process in the presence of wood during the preparation of these factors should give full consideration to maximize the retention and effective ingredients. [Keywords:] costas, costunolide, lactone dehydrogenase, factors Woody as woody species Asteraceae cloud woody Aucklandia lappa Decne. The dry root, mainly produced in Yunnan, Sichuan, is a drug commonly used to treat gastrointestinal disorders. The two main active ingredient is costunolide and lactone dehydrogenase, belong to the sesquiterpene lactones, with a spasm, relaxation of smooth muscle [1], can protect the gastric mucosa, inhibit the occurrence of ulcers [2], and have obvious effect of choleretic and so [ 1], is the main indicator of quality control wood. In the conventional extraction methods, boiling water, mainly wood, to mention volatile oil, alcohol percolation method, with modern technology, supercritical CO2 extraction method is also more are reported in the literature [3,4]. the author of the study found wood, water and ethanol extracted