Familial medullary thyroid carcinoma 1 case.docVIP

 PAGE \* MERGEFORMAT 7 Familial medullary thyroid carcinoma 1 case [Keywords:] medullary thyroid carcinoma Thyroid cancer is the most common thyroid cancer [1], accounting for about 1% of systemic cancer [2], thyroid cancer is a very common endocrine malignancy, most of the pathological type of differentiated thyroid cancer. The Medullary thyroid cancer is the most rare form of cancer, often family history. medullary carcinoma of the medium degree of malignancy, lymph node metastasis occurs early, so early removal by surgical removal of cervical lymph nodes or both, for patients with good prognosis. This reported 1 case of familial medullary thyroid carcinoma. 1 Clinical data Patients, female, 42 years old. Because of cervical tumor six months, on August 9, 2001 admission. The patient lived for generations in the high incidence of goiter, 2 siblings, his brother was 5 years ago due to medullary thyroid carcinoma in Shanghai surgery, his mother died of thyroid cancer 8 years ago. checkup: P 88 beats / min, BP 14/9kPa, generally good, facial flushing, and neck lymph nodes did not reach the right thyroid can reach a diameter of 3cm quality hard nodules, left no time. neck X-ray tube without pressure, chest and abdominal B ultrasound, ECG were normal. Laboratory tests: serum calcium 2.6mmol / L, phosphate 1.52mmol / L, potassium 4.5mmol / L, T3 1.9ng/mL, T4 96ng/mL. thyroid scan: tips slightly enlarged thyroid, right lobe of the “cold nodule.” Surgical exploration findings: on August 15, 2001 cervical plexus anesthesia in surgery, the right lobe surgery see that there is a 3cm 2.5cm 2.5cm sclerosis, also within the left lobe and a 0.5cm 0.3cm 0.3 cm induration, boundaries less clear, there are two paratracheal lymph nodes, suspected thyroid cancer surgery, then rapid removal of some tissue pathological examination confirmed bilateral thyroid cancer. that general anesthesia, the thyroid gland on the right lines and cervical lymph node excision cle