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Flurbiprofen fentanyl after orthopedic surgery under combined anesthesia analgesia
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Flurbiprofen fentanyl after orthopedic surgery under combined anesthesia analgesia
[Abstract] Objective To observe flurbiprofen fentanyl combined block for postoperative analgesia following orthopedic surgery effectiveness and adverse reactions. Methods for elective orthopedic surgery 100 patients were randomly divided into two groups: control Group of surgery was 0.1 mg intravenous loading dose of fentanyl, followed by PCIA pump, pump drugs fentanyl 1.2 mg + droperidol 5 mg, 100 ml/48 h; experimental group patients completed the intravenous injection of flurbiprofen 50 mg as loading dose followed by PCIA pump, pump drugs flurbiprofen 50mg + droperidol 5 mg + fentanyl 0.5 mg, 100 ml/48 h. within 24 h of postoperative pain score (VAS), sedation score (SS) and adverse reactions. Results There was no significant difference between the sedative effect (Pgt; 0.05), control group, high incidence of adverse reactions in the experimental group (P lt;0.05), sedation score (SS) is lower than the test group. Conclusion flurbiprofen fentanyl combined block postoperative analgesia following orthopedic surgery well, and reduce the amount of fentanyl, a low incidence of adverse reactions, can improve the quality of analgesia.
[Keywords:] flurbiprofen; fentanyl; joint block; orthopedic surgery; pain
In recent years, non-steroidal anti-inflammatory analgesic drugs, the role of postoperative analgesia in rapid injection flurbiprofen (flurbiprofen axetil injection, trade name Kai Fun) has targeted analgesic effects by inhibiting prostaglandin (prostaglandin, PG) synthesis, play a sedative effect [1]. traditional opioid analgesia exact, but its poor tolerability, adverse effects such as nausea, vomiting, respiratory depression has drawn wide attention. So the new non-steroidal antiinflammatory analgesics for postoperative pain treatment is a new development trend in recent years, this paper evaluation of flurbiprofen observed fentanyl combined block
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