Fluoxetine Treatment of 54 cases of malignant tumors with depression - anxiety status of the clinical analysis.docVIP

 PAGE \* MERGEFORMAT 9 Fluoxetine Treatment of 54 cases of malignant tumors with depression / anxiety status of the clinical analysis Study: Xinhua Shen Liqing Bo Zhang Haibing [Abstract] [Objective] fluoxetine treatment of malignant tumors associated with anxiety / depression in patients with efficacy and impact on quality of life. [Methods] Diagnostic criteria and classification of mental disorders by the Chinese Version 3 (CCMD 3), using Chinese secret Hamilton Anxiety Scale (HAMA 14) and Depression Scale (HAMD 24) in the diagnosis of patients with cancer-related depression scores in patients with mild to moderate depression fluoxetine 20 ~ 40mg / d, for 8 weeks, WHO life Quality Assessment Scale (WHO QOL) evaluation of the quality of life improvement, side effects scale (TESS) and related laboratory tests to evaluate the safety. [Results] 2w end of the scale scores were improved compared with before treatment, treatment 4 ~ 6w end of the score and the treatment differ significantly (P lt;0.01), treatment 8w end effective rates were 92.4% and 96.3%, quality of life improved significantly, adverse reactions were mild, without special treatment. [Conclusion] some cancer patients with anxiety and depression, antidepressant fluoxetine in the treatment effect is significant. [Keywords:] cancer, depression / anxiety, quality of life, fluoxetine Abstract: [Objective] To study the effect and reliability of fluoxetine on depression and symptoms in cancer patient, and to assess the overall quality of life before and after treatment. [Methods] We treated 54 cancer patients with depression by Fluxetine for 8 w, at the same time, evaluated their emotion state, change of quality of life and the adverse effect with HAMD, HAMA, TESS and laboratory tests. [Results] After 8 w, patients’ scores of anxiety and depression decreased significantly from the baseline, effective rates were 82.4% and 96.3% respectively. 3 domains of quality of life (physiology, psychology