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Focal nodular hyperplasia of liver pathology and differential diagnosis
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Focal nodular hyperplasia of liver pathology and differential diagnosis
[Abstract] Objective To investigate the hepatic focal nodular hyperplasia (FNH of the pathological features, histological classification and differential diagnosis. Methods 40 cases of hepatic focal nodular hyperplasia of the clinical data, and using HE staining paraffin-embedded light microscope to observe the histological features. Results 40 cases of hepatic focal nodular hyperplasia patients, 28 females, 12 males, aged 18 to 62 years, mean age 41.3 years before surgery in all cases there was no history of hepatitis , AFP negative, 25 cases of histologically classic, with a central fibrous scar characteristic, and distorted by the fibrous connective tissue composed of blood vessels dilated capillaries .8 cases, the rest is mixed and the type of adenomatous hyperplasia . Conclusions Hepatic nodular hyperplasia of liver cells is an abnormal response to local vascular hyperplasia, is not a true tumor, mainly nodular adenomatous hyperplasia of the liver, liver anaplastic nodular hyperplasia, fibrolamellar carcinoma of the liver and liver cell adenoma identification.
[Keywords:] of hepatic focal nodular hyperplasia, histological type, pathological diagnosis, differential diagnosis
[Abstract] Objective To study the pathological features and histopathological type and differential diagnosis of hepatic focal nodular hyperplasia (FNH.Methods The clinicopathological characteristics of 40 cases of FNH were studied.All were evaluted by use of paraffin embedded sections and HE staining before light microcope observation.Results There were 28 females and 12 males FNH patients whose age were from 16 to 62 years (median 41.3, all alpha-fetoprotein was negative and had no hepatitis history.25 cases were classic type showed characteristic central stellate fibrotic scar, composed of fibrous connestive tissue and tortuous blood vessels.8 cases were telangiectic type, the lef
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