Gynostemma on the morphology of mouse skin aging.docVIP

 PAGE \* MERGEFORMAT 6 Gynostemma on the morphology of mouse skin aging [Abstract] Objective: To investigate the Gynostemma on the morphology of mouse skin aging effects. Methods: 60 12-month-old Kunming mice were randomly divided into 3 groups: control group, Gynostemma low dose group (A group), Gynostemma high-dose group (B group); control group were coated with excipients, A group with 4% Gynostemma cream coated with, B group were coated with 16% Gynostemma cream. 40 days after the biopsy in organizational learning. Results: Compared with control group, high-dose Gynostemma can significantly thicker dermis, collagen fibers thick, closely arranged, elastic fibers increased; low doses of Jiaogulan degree of influence of aging on the skin is not significant. Conclusion: High doses of Gynostemma pentaphyllum on the morphology of mouse skin aging effects of increased synthesis of collagen fibers, elastic fiber degeneration reduced.  [Keywords:] Gynostemma; aging; skin; morphology; image analysis The skin in the body surface is the body most vulnerable to the aging process exposed organs. Therefore, prevention and delay of skin aging has become one of the hot life-science research [1]. In recent years, studies have shown that: Gynostemma (Fiveleaf Gynostemma Herb) are rich in ginseng saponins and a variety of essential amino acids and trace elements, with Qi spleen, kidney Onyang, anti-aging, anti-fatigue, Yang Xin soothe the nerves, nourishing strong, pharmacological detoxification and other functions, better effect on a variety of diseases. But for external Gynostemma whether the morphological changes caused by aging in the skin-reported, this study has conducted some preliminary studies. 1 Experimental Materials and methods 1.1 Experimental animals and grouping healthy Kunming mice were 60 kinds of 12-month-old, weighing 40 ~ 45g. Were randomly divided into 3 groups: control group, Gynostemma low dose group (A group), Gynostemma high-dose group (B g