HA IV-C P Ⅲ NP LN joint detection in the liver of analysis.docVIP

 PAGE \* MERGEFORMAT 6 HA IV-C P Ⅲ NP LN joint detection in the liver of analysis [Abstract] Objective To investigate serum hyaluronic acid (HA, Ⅲ procollagen peptide (P Ⅲ NP, Ⅳ collagen (IV-C, laminin (LN diagnosis of liver diseases. Methods ELISA 50 healthy persons , 50 patients with fatty liver, 50 patients with liver cirrhosis of HA, IV-C, P Ⅲ NP, LN. the result of fatty liver group and the cirrhosis group, HA, P Ⅲ NP, IV-C and LN was significantly higher than the normal group (P lt;0.05 or P lt;0.01, and the liver cirrhosis group was significantly higher than (P lt;0.05 or P lt;0.01. Conclusion liver disease patients with varying degrees of hepatic fibrosis levels, combined detection of HA, PC Ⅲ, IV-C and LN content can be hepatic fibrosis and liver better reflect the extent of material damage, and can provide the basis for clinical diagnosis and treatment. [Keywords:] Detection of liver disease of liver fibrosis As people’s living standards improve, alcoholic liver disease, fatty liver disease rates continue to rise; in foreign countries, alcoholic liver disease, has been high incidence of fatty liver, liver fibrosis is diffuse, excessive extracellular matrix deposition, deposition of extracellular matrix which is more or less a direct consequence of the degradation is common in many liver diseases, the pathological process of liver fibrosis prevention and treatment research is a hot spot at home and abroad. for the effective treatment of patients with early stage, we in groups HA, IV-C, P Ⅲ NP, LN joint detection, the results are as follows. 1 Materials and Methods 1.1 General information collected in our hospital from August 2009 to August 2010 in our hospital healthy patients with fatty liver, cirrhosis patients, 50 people. Aged 22-65 years, mean age (38.3 + -16.4 years old, all patients with liver disease were confirmed by history, signs, laboratory tests and imaging diagnosis. all subjects caught fasting venous blood 5ml, the s