Half dose verteporfin photodynamic therapy in acute central serous chorioretinopathy.docVIP

 PAGE \* MERGEFORMAT 20 Half dose verteporfin photodynamic therapy in acute central serous chorioretinopathy [Abstract] Objective: To observe the half dose verteporfin photodynamic therapy (photodynamic therapy, PDT treatment of acute central serous chorioretinopathy (central serous chorioretinopathy, CSC short-term effect. Methods: 2009 04/2009 09 diagnosed with acute CSC 12 eyes of 12 patients, half of the amount of a single line of verteporfin (3mg/m2 photodynamic therapy, preoperative and postoperative 1,4,12 wk for three-dimensional optical coherence tomography (3D OCT testing, and before surgery, 4wk and 12wk after retinal fluorescein angiography (FFA, choroidal angiography (ICG and fundus autofluorescence (FAF examination, observation of the efficacy and safety of treatment. Results: Preoperative 3D OCT show serous neuroepithelial detachment, angiography exist in kind or the smoke kind of ink leakage and choroidal vessel Niuqu expansion of diffuse fluorescence leakage after 1wk, 3D OCT 6 eyes subretinal fluid absorption after 4wk 9 when displayed in the OCT, exudate Wanquan absorption, 7 eyes showed fluorescein leakage in the FFA in the disappearance of three to reduce leakage, 9 appear distorted in the expansion of ICG choroidal vessel diameter returned to normal, three diameter slightly improved, and nine in the preoperative leakage abnormal autofluorescence point returned to normal, after 12wk, only 1 case has not fully absorbed subretinal fluid, exudates more than 11 were completely absorbed, 12 eyes showed no abnormalities in the fluorescence imaging of leakage, in the FAF display of the original slurry emerging in the region point out the strong autofluorescence sheet scattered points. treatment 12wk, visual acuity increased from a preoperative average of 0.43 to 0.8, 2 of which no significant change in visual acuity after surgery. follow-up period 12 were not seen any adverse reactions. CONCLUSION: half dose verteporfin PDT treatment of acute C