Happy Soft Capsules Quality Control of.docVIP

 PAGE \* MERGEFORMAT 12 Happy Soft Capsules Quality Control of Author: Deng Weizhe, Yang Zhixin Chang Pei Guang-jie Chen Shuang flood control [Abstract] Objective To establish a Happy Capsules quality standards. Thin Layer Chromatography (TLC) identification of the legal nature of Bupleurum, white peony root, angelica, licorice; using high performance liquid chromatography (HPLC) Determination of paeoniflorin, ferulic acid content. TLC chromatography can result in the detection of Bupleurum, white peony root, angelica, licorice; paeoniflorin at 51 ~ 340 μ g * ml-1 within the framework of a good linear relationship, r = 0.999 9, the average recovery was 98.2 %, RSD = 1.41% (n = 6). Ferulic acid 41.6 ~ 208 μ g * ml-1 within the framework of a good linear relationship, r = 0.999 9, the average recovery was 100.5%, RSD = 1.37% (n = 6). Conclusion The method is simple and accurate, can be used as the index of quality control standards. [Keywords:] Happy Soft Capsule paeoniflorin ferulic acid, HPLC Abstract: ObjectiveTo establish the standard of Xiaoyao Capsula Mollis. MethodsRadix bupleuri, Radix Paeoniae Alba, Radix Angelicae Sinensis, Radix Glycyrrhizae in the preparation were identified by TLC; Paeoniflorin and ferulaic acid were determined by HPLC. ResultsRadix bupleuri, Radix Paeoniae Alba, Radix Angelicae Sinensis, Radix Glycyrrhizae could be identified by TLC. Paeoniflorin showed a good linear relationship at a range of 51 ~ 340 μ g * ml-1, r = 0. 999 9, the average recovery of paeoniflorin was 98.2%, RSD was 1.41% ( n = 6). Ferulaic acid showed a good linear relationship at a range of 41.6 ~ 208 μ g * ml-1, r = 0.999 9, the average recovery of ferulaic acid was 100.5%, RSD was 1.37% (n = 6). ConclusionThe methods are simple, accurate and reproducible. Keywords:: Xiaoyao Capsula Mollis; Paeoniflorin; Ferulaic acid; HPLC Xiaoyao pill for Han Zhang Zhongjing book ‘Treatise on Typhoid Fever’ in the Sini San and ‘Golden Chamber’ in the Evolution of the