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Happy Lou Bei capsule on the ultrastructure of hyperplasia of mammary glands
PAGE \* MERGEFORMAT 8
Happy Lou Bei capsule on the ultrastructure of hyperplasia of mammary glands
[Abstract] Objective: To explore the Happy Lou shell capsule on the ultrastructure of hyperplasia of mammary glands. Methods: 50 rats were randomly divided into normal group, model group, Happy Lou shell capsule low-dose group (low-dose group), Happy Lou shell capsule high dose group (high-dose group) and Rupixiao groups of 10 . Electron microscopy the ultrastructure of rat mammary gland. Results: The treatment of mammary hyperplasia in rats after administration of the extent of the lesions than those in model group significantly reduced, in which high-dose group, Rupixiao similar group and normal group, followed by low-dose group. Conclusion: The Happy Lou shell capsules can inhibit estradiol benzoate in rats induced mammary hyperplasia, and a dose effect.
[Keywords] hyperplasia of mammary glands; Happy Lou shell capsules; Rupixiao
Happy Lou shell capsules by Angelica, Bupleurum, Trichosanthes, Zhejiang Fritillaria, mountain Arrowhead composed of 10 flavor of Chinese medicine, with Shugan Qi, phlegm Sanjie other effects, clinical efficacy of treatment of hyperplasia of mammary glands quite good. In order to explore its mechanism, we conducted a series of studies, it is their right ultrastructure of hyperplasia of mammary glands reported as follows.
1 Materials and methods
1.1 Experimental Materials
1.1.1 Experimental Animal Wistar rats 50, female non-pregnancy weight (200 ± 10) g, by the Experimental Animal Center of Shanxi Medical University.
1.1.2 Experimental Drug Happy Lou shell capsules: from Shanxi Medical College Hospital preparation room to offer each and weight 0.5 g, drugs net content 0.4 g; Rupixiao films: Liaoning Huanren in pharmaceutical production, batch number: 021,109, Each weight 0.5 g, to the sugar, the crushed over 100 mesh sieve back; estradiol benzoate injection (hereinafter referred to as E2), amino acids produced in Tianjin, batch
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