Hong Shu drink tablet by TLC and determination of.docVIP

 PAGE \* MERGEFORMAT 10 Hong Shu drink tablet by TLC and determination of [Abstract] Objective To establish the Hong Shu Dispersible Tablets drinking quality standards. Methods TLC prescription bergamot, borneol were identified, by high performance liquid chromatography preparation of the content of naringin column was AichromBond- AQ-C18 (4.6 mm × 150 mm, 5 μm), the aqueous phase as mobile phase A, acetonitrile as mobile phase B, in which the water phase from the water - acetic acid (100:1), with by mobile phase A (%): mobile phase B (%) = 84%: 16% for elution, detection wavelength was 283 nm, column temperature 30 ℃, the flow rate 1 mL / min. the results of TLC and specific, the linear range of naringin 0.120 6 ~ 0.603 μg, r = 0.999 9, the average recovery was 97.90%, RSD = 1.76% (n = 5). Conclusion The method is simple, accurate, reproducible, and can be used as the quality of Hong Shu drink tablet control standards. [Keywords:] Hong Shu drink tablet, naringin, bergamot, borneol, quality standards Abstract: Objective To establish the quality standard for Xiangshuyin Dispersible tablets. Methods Fructus citrus sarcodactylis and Borneolum syntheticum in the prescription were identified by TLC. The content of the total Naringin was determined by HPLC. The column of AichromBond-AQ-C18 (4.6 mm × 150 mm, 5 μm) was used. The mobile phase was mobile phase A-mobile phase B (84:16), mobile phase A was Water-Acetic Acid (100:1), mobile phase B was Acetonitrile, at the flow rate of 1.0 mL / min, the column temperature of 30 ℃, and peaks were detected at 283 nm. Results The study on the quality control showed that the characteristic of identification by TLC was distinct and highly specific. The linear range of Naringin was 0.120 6 ~ 0.603 μg, r = 0.999 9, the average recovery was 97.90%, RSD = 1.76% (n = 5). Conclusion The method was easy to operate with accurate result and good reproducibility. It can be used effectively for the quality control of the preparati