Human papillomavirus infection on the investigation and Load and the relationship between CIN lesions.docVIP

 PAGE \* MERGEFORMAT 11 Human papillomavirus infection on the investigation and Load and the relationship between CIN lesions Of: Zhouhong Rong, Wang Zhongying, Li Haichuan, Gong Bo [Abstract] Objective HPV infection in our hospital around positive rate, HPV-DNA infection for the clinical treatment of cervical cancer early detection of cervical cancer and provide a laboratory basis. Methods HC-Ⅱ hybrid capture test to our hospital HPV infection in women in check, so low, high grade squamous epithelial damage relations with the HPV-DNA load research, Department of retrospective analysis of all cases, data collected from the Pap smear Ⅱ (PAP Ⅱ) level and above, ASC- US or low, high grade squamous epithelial damage, with the HC-Ⅱ Hybrid Capture high-risk types HPV13 virus, according to the amount of virus detection is divided into negative, low, medium and high load, chi-square test and logistic regression to analyze the data, case A total of 3593 cases. results in a high degree of viral load and the extent of damage was significantly correlated (P = 0.022 lt;0.05), regression analysis further confirmed, HPV load and the level of closely related tissue damage, particularly highly damage (P = 0.016 lt; 0.05) and in the high viral load were significant but low degree of damage, except (P = 0.140gt; 0.05). Conclusion The high-grade squamous epithelial damage and the high degree of risk was closely related to viral load. [Key Words] high-risk human papillomavirus (HPV-DNA); infection; viral load; cervical intraepithelial neoplasia (CIN) [Abstract] Objective To investigated HR-HPV infection rate in the district near our hospital and high-grade cervical dysplasia correlates with high viralload of HR-HPV.Methods HR-HPV is recognized as the primary cause for the development of cervical cancers and their precursor lesions. Cases were retrospectively selected to include patients with a prior cytological diagnosis of PAP Ⅱ, ASC-US, lower or higher grade squamous