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Hypercoagulability disease and ulcerative colitis-related analytical fate
PAGE \* MERGEFORMAT 4
Hypercoagulability disease and ulcerative colitis-related analytical fate
[Abstract] Objective: To explore the D-dimer (D-dimer) and ulcerative colitis (UC) disease activity whether there is relevance. Methods: UC patients with active stage study of 127 cases as a control group, 53 patients in the treatment of all subjects before and after treatment and isolated mining 3 mL venous blood plasma. To immune turbidimetry of serum D-dimer. Results: The period of D-dimer in patients with UC was significantly higher. Anticoagulant treatment group after treatment clinical activity score better than the group without anticoagulant therapy, after anticoagulant treatment in patients with D-dimer were significantly lower than without the anticoagulant treatment group. Conclusion: D-dimer plasma concentration in patients with active UC grading the condition of positive correlation. With active UC in patients with thrombosis in a significant pre-condition to improve the amount of low molecular weight heparin in patients with high blood coagulation state of the effective treatment of active ulcerative colitis.
[Keywords:] Ulcerative colitis; D - dimer; coagulation
Ulcerative colitis (ulcerative colitis, UC) is a kind of cause is not clear that the rectum and colon of chronic non-specific inflammatory bowel disease. Duocheng recurrent chronic disease process, are currently considered to include environmental, immune and genetic, psychological and many other factors, due to [1]. In recent years, its incidence has increased, also many reports of critically ill patients. Studies have found that, UC patient’s blood showed hypercoagulable state, concurrent thromboembolic disease were not rare, autopsy report, up to 39%, and became the lead UC’s third-largest cause of death in patients [2,3]. In this study patients with active UC and non-anticoagulant use of anticoagulation before and after treatment and health of the blood of the control group D - dimer (D
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