Implantation of calcium sulfate bone repair bone defects in rabbits tolerant mechanical analysis.docVIP

 PAGE \* MERGEFORMAT 15 Implantation of calcium sulfate bone repair bone defects in rabbits tolerant mechanical analysis Author: Chen, Tian Xuezhong, Zhang Boxun, Xue-Zhong Yu, Ai-Yuan Wang, Hu Chengdong, Cui, Pei-Fu Tang, Yan Abstract [Objective] To investigate the in vivo implantation of calcium sulfate bone defects after the biomechanical properties of the activities. [Methods] To establish a rabbit distal femur bone defect model of an inclusive, respectively, and the citric acid of calcium sulfate tablets fill Osteoset  repair, 3,6,13 weeks after animals were killed for general observation and experimental analysis of mechanical pressure Au. [Results] after rabbits campaign freely, no limp, mental and eating normal wound healing is good, cut off stitches automatically. Drawn after the animals were killed when the organization was no joint effusion and the surrounding tissue inflammatory response. Biomechanical analysis showed that: After 3 weeks, artificial bone to repair bone defect of anti-compressive strength, elastic modulus higher than normal levels of femoral condyle; defects after 6 weeks of anti-compressive strength, modulus of elasticity than 3 weeks after operation when the reduction in the level, but lower than the level of femoral condyle; after 13 weeks when the defect resistance to compression strength, elastic modulus increased level when compared to 6 weeks, and close to the normal level of femoral condyle. At different time points, bone graft area showed a comparative analysis of mechanical strength of two kinds of artificial bone was no significant difference, but they are significantly higher than the corresponding control group. [Conclusion] The absorption of calcium sulfate degradation, defect bone repair process, its inclusion has some mechanical defect in bone supporting role. Citrate of calcium sulfate can play a considerable role in Osteoset  film. Keywords: bio-active materials; citrate of calcium sulfate