Infants and young children the safety of drugs.docVIP

 PAGE \* MERGEFORMAT 29 Infants and young children the safety of drugs 【Abstract】 Objective To investigate the drug safety of infants and young children. See more on the domestic relevant literature data collation, analysis and synthesis. Results (1) to avoid the application of prohibited drugs. (2) You need to use caution drugs should be under the guidance of physicians in clinical medicine, and should closely observe the patient’s condition and treatment of drug reactions. Conclusion In order to infant health, medicine for its selection, the combination according to the characteristics of drugs in patients with specific conditions, timely use of safe, effective, adequate and reliable drugs. Keywords: infant drug safety Infants and young children is from 28 days to 3 years of age in children, although children in this period significantly more mature newborns, but the drug is not simply to reduce the adult dose. Because the tissue distribution of drugs in children are different from adults, the first is the permeability of cell membrane are different; second protein binding force of change; third fluid distribution differences. And the development of pediatric liver enzyme system is not yet mature, and renal function is imperfect, its effective renal blood flow and glomerular filtration rate lower than those of adults, tubular secretion, urine concentration, sodium ion-exchange and acid-base balance functions are bad , age, the smaller the more imperfect [1]. So there are a variety of different adult drug reaction. In addition to infants and young children and therefore patients require timely and correct treatment, are familiar with the general drug laws, but also to grasp the characteristics of pediatric medicine. Following is the author of some commonly used drugs and the relationship between the infants and young children are summarized below. An antibiotic, sulfa, quinolones 1.1 penicillins are commonly