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Injection of Ginkgo biloba on microalbuminuria in early diabetic nephropathy of
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Injection of Ginkgo biloba on microalbuminuria in early diabetic nephropathy of
Of: Zhang Haisheng, Zhao Lijuan, Peng Baohong
[Keywords:] diabetic nephropathy, 24 h urinary protein excretion, ginkgo leaf injection
In recent years, the author uses ginkgo leaf injection combined with benazepril tablets in treatment of early diabetic nephropathy, and to observe its effect on urinary albumin, are reported below.
1 Materials and Methods
1.1 General Information
Select January 2007 -2009 in our hospital in January of 65 patients with early diabetic nephropathy patients, 35 males and 30 females, age (50.2 + -8.5 years), duration (9.5 + -7.5) years. By Random number table, 35 patients were randomly divided into treatment group and control group of 30 patients, 2 groups in age, gender, body mass index, duration, etc. were not significantly different (Pgt; 0.05), comparable.
1.2 Diagnosis and inclusion criteria
All patients meet the WHO 1999 diagnostic criteria of diabetes issued in the early diagnosis of diabetic nephropathy by Mogensen of the DM classification criteria for the DN-Ⅲ period, 24 h urinary albumin in the 30 ~ 300 mg, 6 months, checked at least 3 times 2 meet the above criteria be confirmed. except for diabetic ketoacidosis, exercise, fever, urinary tract infection, menstruation, primary and secondary renal disease and other causes of the proteinuria.
1.3 Treatment
Group 2 patients were treated with diabetic diet, with high-quality low-protein diet, exercise, hygiene education, lowering blood sugar and other conventional treatment, both oral benazepril 10 mg, 1 times / d. The treatment group received injection of Ginkgo biloba (Heilongjiang Province Treasures Island Pharmaceutical Co., Ltd. production, 5 mL / Support) 20 mL by adding 250 mL normal saline infusion, 1 / d, 14 d as a course of treatment, the results observed after 2 courses.
1.4 OUTCOME MEASURES
Before treatment and after treatment were
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