Infants after open heart surgery capillary leak syndrome.docVIP

 PAGE \* MERGEFORMAT 11 Infants after open heart surgery capillary leak syndrome Author: moan wins, Mo Far East, Zhou Guang-quan Keywords: Cardiac surgery; cardiopulmonary bypass; capillary leak syndrome Capillary leak syndrome ((capillary leak syndrome, CLS) is a good fat in infants after open heart surgery with cardiopulmonary bypass for severe complications, mortality is high, domestic and foreign literature related to small, in the heart monograph rarely referred to the disease, so clinical on the lack of adequate understanding and awareness of the disease. Domestic addition to the heart of several large centers, infant open heart surgery with cardiopulmonary bypass was basically at the stage of enlightenment, for the complications of understanding of few, and that the pathophysiology and treatment of complications, they are special, so it’s necessary to write such articles. 1 Definition CLS is due to capillary endothelial cells after cardiopulmonary bypass damage, vascular permeability increase, a large number of plasma protein infiltration into the tissue space, which appears hypoproteinemia, hypovolemic shock, acute renal ischemia, severe edema and other tissues and organs of clinical the performance of a group of syndromes. 1996 Seghaye such as the definition of CLS for the postoperative cardiac surgery patients occurred within 48h of non-cardiac systemic edema, pleural effusion, ascites, blood pressure instability, blood volume necessary to supplement the state. 2001 Stiller and so the definition of CLS for cardiac surgery occurred within 48h after non-cardiac systemic edema, pleural effusion, ascites, weight gain over 10%. 2 Pathogenesis The pathogenesis of CLS is unknown, most believe is a cardiopulmonary bypass (cardiopulmonary bypass, CPB), the systemic inflammatory response, a large number of inflammatory mediators, resulting in systemic capillary endothelial cell damage, as well as colloid osmotic press