Insulin therapy and treatment of newly diagnosed type 2 diabetes -cell function.docVIP

 PAGE \* MERGEFORMAT 6 Insulin therapy and treatment of newly diagnosed type 2 diabetes -cell function [Abstract] Objective To observe the early insulin therapy in newly diagnosed type 2 diabetes mellitus (T2DM) patients with blood glucose control and cell function. Methods in early diagnosed type 2 diabetes treatment by insulin treatment group were divided into 15 d, 60 d 2 groups. observed two groups before and after treatment blood glucose and pancreatic -cell function. Results 2 patients after treatment of islet function were improved, and the 60 d group than in the 15 d was significantly improved. Conclusion Insulin therapy can significantly improve type 2 diabetes -cell function . [Keywords:] diabetes, type 2; insulin; islet B cells Early severe hyperglycemia in type 2 diabetes mellitus (T2DM) patients treated with insulin to control high blood sugar and reverse the “glucose toxicity” on the islet -cell dysfunction has become the new trend of treatment of T2DM [1]. Based on the early insulin after follow-up treatment of patients, effect of insulin therapy on glycemic control and -cell function. 1 Subjects and methods 1.1 The object of our hospital in June 2005 ~ December 2008 in patients with newly diagnosed type 2 diabetes, 40 patients, 25 males and 15 females, mean age (41 + -8 years). By 1999 WHO diagnostic criteria for diabetes diagnosis. FPGgt; = 11 mmol / L, 2hPGgt; = 16 mmol / L HBA1cgt; = 10%. eliminate stress, severe liver and kidney disease, heart failure, ketoacidosis and other diseases that affect glucose metabolism. by insulin treatment time Patients were divided into 15 d 60 d 20 cases and 20 cases of group 2 patients age, sex, diabetes duration, BMI, WHI, blood pressure and blood sugar was no significant difference. 1.2 Methods (1) treatment: patients admitted to the diet only after the first 2 days testing indicators: FPG, FIns, FC P, HbA1c, 2hC P, 2hIns liver and kidney functions. Subsequent to insulin therapy, to Novol