Jie Ling bacteria solution method for the determination of metronidazole Improvement.docVIP

 PAGE \* MERGEFORMAT 10 Jie Ling bacteria solution method for the determination of metronidazole Improvement [Abstract] bacteria spiritual solution to improve cleaning method for the determination. Methods: Metronidazole in the ether and hydroxyl ethyl benzene, there are differences in solubility, extraction with ether hydroxyl ethyl benzene. Results: The exclusion of the hydroxyl ethyl benzene, caused by the wave length of metronidazole shift so that the results relatively high interference, the average recovery was 99.31%, RSD = 0.68% (n = 6) Conclusion: This method is simple, rapid and accurate can be used to improve the standard method for the determination of the original. [Keywords:] Jie Ling solution, with metronidazole determination of bacteria to improve [Abstract] Objective: To improve the content determination of Jiejunling solution.Methods: According to the difference of the solubility in aether between metronidazole and ethyl hydroxybenzoate wether was used to extract ethyl hydroxybenzoate.Results: This method eliminated the interference of the imfluence of ethyl hydroxybenzoate, such as hypsochromic shift of wave and a bit higher of the results. The average recovery was 99.31%, RSD = 0.68% (n = 6). Conclusions: This method was simple, fast and accurate, and was suitable for improving the original criteria. [Keywords:] Jiejunling solution; Metronidazole; Content Determination; Improvement Ling Jie bacteria solution is self-made topical preparations in our hospital, used clinically for many years, mainly used for inflammatory skin infections, acne and hair follicle infections caused by worms. Main components of the preparation of metronidazole and gentamicin, the original information submitted by UV spectrophotometric determination of metronidazole concentration [1] 123, the result is accurate, and no interference with other components. Because the process easy to use and storage of mildew, so the addition of preservatives in the original presc