Local skin inflammation and wound repair.docVIP

 PAGE \* MERGEFORMAT 13 Local skin inflammation and wound repair [Abstract] This paper focuses on the body skin in the repair process after injury involved in the local inflammatory response. Summarize the findings in this field to date and scientific knowledge, mainly involving the skin repair process after injury no local inflammation, moderate inflammation abnormal inflammatory response and the three situations. when some special period of embryonic skin (such as human embryos only 22 to 24 weeks in the embryonic skin of mice only in the 16-day fetal skin), while the repair process after injury without the need related to inflammation, because these hair follicles and sebaceous glands of skin renewal, and other accessories are fixed with no scar formation of the normal dermal matrix; When the skin hair follicles and sebaceous glands and other accessories not update capability, but there are still intact after the skin lesions and hair follicles sebaceous glands and other accessories, a moderate inflammatory response is beneficial wound healing; when the local skin inflammation in the event of imbalance, the imbalance caused repair - scar formation or wound healing. [Keywords:] skin; injury; inflammatory reaction; wound healing Abstract: This article focuses on some characteristics between the local inflammatory reactions and wound regenerations in skin, which involves the non inflammatory reaction, suitable inflammatory reactions and abnormal inflammatory reactions.Non inflammatory reaction occurs in the special period (at around 22th to 24th weeks of gestation in the human fetus and at about 16th embryonic day for mice) wound regeneration, because these skins have the characteristics of renewal of skin appendages such as hair follicles and sebaceous glands, in addition to the restoration of a normal dermal matrix and no scar. For the suitable inflammatory reactions, the skin appendages have no renewal abilities exept the useful functions of acceler