3种大环内酯类抗生素治疗小儿支原体肺炎的成本-效果分析.pdfVIP

3 种大环内醋类抗生素治疗小儿支原体肺炎的成本…效果分析 那建生气宁夏医学院附属医院制别科，银川市 750004) 中圈分提号 R956 文献标 i只码 C 文章编号 1001-0408(2007)11-0806-02 摘 要 目的:比较 3 种大坏内附类抗生素治疗小儿支原体)J;jr炎的疗效:il成本 效果。方法 :89 例患儿分成 A 、巴、 C 组，分别给予 阿奇莓索、克拉霉素、红霉素治疗，并进行成本→效采分析。结采 :A 、日、 C 纽总成本分别为 103.30 、 180.70 、 50.40 元，总有效率分别 为 93.94% 、 93.10% 、 92.59%(P 0.0的，不良反应发生率分别为 15.15% 、 20.69% 、 40.74%(P0.01) 。结论:阿奇霉素是治疗小 儿支原体肺炎的较好药物。 关键词 小儿支原体肺炎;阿奇~素;克拉霉素:红霉素;成本…效采分析 Cost - Effectiveness Analysis of Three Macrolides in Treatment of Mycoplasmal Pneumonia in Children XING Jiansheng(The Affiliated Hospital of Ningxia Medical College , Yinchuan 750004,China) ABSTRACT OBJECTIVE: 丁o compare the curative efficacy and cost effectivene柿 of three macrolides in treatment of my而 coplasmal pheumonia in children.METHODS:89 children(patients) wer巳 divided into groups A, B and C, and given respectively Azithromycin , Clarithromycin, and Erythromycin for treatment .A cost → effectivenes日 analysis was then conducted. RESULTS: 丁he total medication costs for groups A , B and C were 103.30 yuan , 180.70 yuan and 50.40 yuan respectively; overall effect rates for the three groups were 93.94% ,93.10% and 92.59%(P0.05) respectively;adverse reaction occurrence rates for the three groups were 15.15% , 20.69% and 40.74% (PO.Ol) respectively .CONCLUSION: Azithromycin is a macrolide agent better in treatmènt of mycoplasmal pneumonia in children. KEY WORDS Mycoplasmal pneumonia in children;Azithromycin;Clarithromycin;Erythromycin;Cost - effectiveness analysis 根据世界卫生组织 (WHO) 与荣国卫生管理中心 (MHS) 月 -2005 年 12 月内 500 份小儿呼吸道感染的黯者，筛选出性 的提议，用药不仅要考虑药物的安全性、有嗷性，问时要考 别、年龄、病程及诊断、治疗用药等均记录完整的病例。建立患 虑经济性的问题。我国肺部感班滥用抗生素现象普遍严重， 者的药历病册，通过电话随谛，上门回访及复诊等方法，获