3种药物用于治疗糖尿病周围神经病变的成本-效果分析.pdfVIP

3 种药物用于治疗糖尿病周围神经病变的成本一效果分析 黄料科女，徐 航，方 芸(南京大学医学院附属鼓楼医院药刑科，南京市 210008) 中团分类号 R956 文献标识码 C 文章编号 1001-0408( 2005) 24 -1877 -02 摘 要 目的:评价 3 种药物用于治疗糖尿病周阁神经病交的成本效果。方法 :60 例患者均分成 A ， B 、 C 组，分别给予前列地尔、 甲钻俗、盐酸丁咯地尔治疗，并进行成本…效果分析。给采 :3 组成本分别为 5290.5 、 2713.0 、 3154.4 元 Imo; 有效率分别为 90% 、 95% 、 85% (P 0.05); 成本节效果比分别为 58.78 、 28.56 、 37.11;3 纽不良反应发生且在元显著性差异 (P0.05) 。结论:应用甲钻 钱和盐酸丁咯地尔比应用前;9]地尔奖经济，而甲钻铭经济性义优于盐酸丁咯地尔。 关键词 糖尿病周围神经病变;前列地尔;甲钻铃;盐酸丁四各地尔;成本…效果分析 Cost - Effectiveness Analysis of 3 Kinds of Drugs for Treatment of Diabetic Peripheral Neuropathy HUANG Lili, XU Hang, FANG Yun(The Affiliated Drum Tower Hospital of Medical School of Nanjing University, Nanjing 210008, China) ABSTRACT OBJECTIVE: To investìgate the cost … effectiveness of 3 kinds of drugs for tr巳atment of diabetic peripheral neuropathy(DPN) . METHODS: 60 patients with DPN were equally dìvided into Group A ，日， and C , each adminìstered with alprostadíl , mecobalamìn ，自nd buflomedil hydrochloride , and the results were analyzed by cost - effectiven巳ss analysis. RE? SULTS: Th 巳 total costs in Group A , B, and C were 5290.5, 2713.0, and 3 154.4 yuanl month , respectively; The ~ffective rates were 90% ,95% , and 85% , respectively(P 0.05) ;The ratios of cost - e{fectiveness ratio were 58.78, 28.56 , and 37.11 , respectively. No sign?ficant difference was found in incidence of adverse drugs r巳actìons(P 0.05) . CONCLUSION: Mecobalamin and buflom日 díl hydrochloride are more economic than alprostadìl , while mecobalamin more econom?c than bu? flomedil hydrochloride. KEY WORDS Diabetic periph巴 ral n巳uropathy; Alprostadil; M巳 cobalamin; Buflomedil Hydrochloride; Cost … effecti veness analysis 糖尿病周围神经病变 (DPN) 是糖尿病常见的慢性并发症和 表 1 3 绍一般情况比较 主要的致残因索之一，发生率达