Mao Ye Ur A preliminary study on the central inhibition.doc

 PAGE \* MERGEFORMAT 11 Mao Ye Ur A preliminary study on the central inhibition Of: Lin Xiaoliang, Luo Chaohua IN TRADITIONAL [Abstract] Objective To study the leaves of Uncaria gross pharmacological effects of the central nervous system. Methods small animal locomotor activity was determined by measuring locomotor activity in mice. With sodium pentobarbital hypnosis subliminal experiments and the threshold dose of pentobarbital sodium induced sleep time was observed by Mao Ye sedative and hypnotic effects of Ur. Results of Ur group (12 g / kg) and low gross Uncaria leaves (6 g / kg), in (9 g / kg), high ( 12 g / kg) 3 dose groups all can reduce the spontaneous activity, so that subthreshold sodium pentobarbital induced sleep sleep the number of doses increased, and extended the threshold dose of sodium pentobarbital sleeping time, and to Mao Ye Ur most obvious effect of high dose group. Conclusion Mao Ye Ur significant central inhibition. [Keywords:] Ur; hair Uncaria leaves; independent activities; hypnotic effect Abstract: ObjectiveTo investigate the pharmacological action of the leaves of Uncaria hirsuta Havil. On CNS. MethodsThe sedative effect and hyponic action of the leaves of Uncaria hirsuta Havil. Could be examined through the mouse locomotor activity experiment, under pentobarbitol sodium threshold dosage-induced sleep experiment and pentobarbitol sodium threshold dosage-induced sleep time experiment.ResultsAfter treated with Uncaria rhyuchophylla. (12g/kg) and the low dose (6g/kg), middle dose (9g/kg) and high dose (12g/kg) of the leaves of Uncaria hirsuta Havil., mouse locomotor activity was reduced, the sleep number of mice which were induced by the sodium pentobabital threshold sleep dosage was incresed, and the sodium pentobarbital-induced sleep time of mice was extended, and the effect in high- dose of the leaves of Uncaria hirsuta Havil. was the most significant. ConclusionThe leaves of Uncaria hirsuta Havil. has significant inhibit