Matrine injection in postoperative concurrent chemoradiotherapy in rectal cancer Efficacy.docVIP

 PAGE \* MERGEFORMAT 9 Matrine injection in postoperative concurrent chemoradiotherapy in rectal cancer Efficacy Of: Yang Ling Lin Lin Fu Hao million Yuan Chuanping [Abstract] matrine injection combined with concurrent radiotherapy and chemotherapy for rectal cancer surgery can significantly reduce the adverse effects caused by radiotherapy and chemotherapy, improving the quality of life of patients, improve patient tolerance to treatment. [Keywords:] matrine injection after concurrent chemoradiotherapy for rectal cancer Common malignant tumor of digestive tract cancer to 5-Fu-based chemotherapy combined with pelvic irradiation is and (or) standard of rectal cancer treatment after surgery. However, patients in the clinical course of treatment because the treatment often adverse affect the quality of life or interruption of treatment. matrine injection of pharmacological experiments and preliminary clinical studies indicate that the drug has anti-cancer, improve immune function, reduce side effects of radiotherapy and chemotherapy and improve the general condition and so on. Therefore, we matrine injection combined with radiotherapy and chemotherapy simultaneously / rectal cancer patients after surgery, the effect is obvious, are reported below. 1 Materials and Methods 1.1 Clinical data in our hospital from May 2007 to June 2009, 60 cancer patients underwent radical surgery, postoperative pathology proved to be and (or) adenocarcinoma or squamous cell carcinoma of the rectum; of which 37 males and 23 females, age range 36 to 68 years, median age 52 years, Karnofsky score greater than or equal to 60 minutes before treatment of heart, liver, kidney function was normal, no significant complications. randomly divided into two groups, treatment group and control group of 30 patients, two groups of patients in stage, Karnofsky score, male to female ratio showed no significant difference on (Pgt; 0.05, with good comparability. 1