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- 2017-05-05 发布于浙江
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Medicine mulberry extracts on type 2 diabetes in rats
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Medicine mulberry extracts on type 2 diabetes in rats
[Abstract] Objective To study medicine mulberry ethanol extract and water extract of type 2 diabetes mellitus (T2DM in rats. Methods fat and high sugar diet intraperitoneal injection of streptozotocin rat model of T2DM copy. The rats were randomly divided into model group, acarbose Pingyang of control, drug mulberry ethanol extract group (20 mg / kg and the water extract group (20 mg / kg, and set the normal control group rats were killed after .4 w in serum glucose, fructosamine, lipid and biochemical indicators (total cholesterol (TC, triglycerides (TG, low density lipoprotein cholesterol (LDL C, high density lipoprotein cholesterol (HDL C), take a fresh determination of liver glycogen, superoxide dismutase (SOD, MDA (MDA. results compared with the control group, model group, blood glucose, fructosamine, MDA, TC, TG, LDL C levels were significantly higher (P lt;0.01), glycogen narrow, HDL C content, SOD activity was significantly lower (P lt;0.05). Compared with model group, the indicators medicine mulberry group significantly improved (P lt;0.05). Conclusion of different extracts of mulberry drugs can reduce blood sugar, increase the antioxidant capacity of rats with T2DM a therapeutic effect.
[Keywords:] drug that Sang-dimensional, type 2 diabetes, antioxidant
[Abstract] Objective To investigate the effect of medicine mulberry different extracts on type 2 diabetic mellitus (T2DM). Methods T2DM model rats were established by intraperitoneal injection streptozotocin (STZ) and high sugar and high lipid diet. Model rats were divided into model, baitangping control, medicine mulberry alcohol extract (20 mg / kgand water extract (20 mg / kg groups and normal control group was selected. Glucose, fructosamine, total cholesterol (TC), triglyceride (TG), low density lipid protein cholesterol (LDL C ) and high density lipid protein cholesterol (HDL C) were detected after 4 weeks. He
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