Mesenchymal stem cell transplantation for treatment of nervous system diseases liver and kidney function in patients with short-term clinical observation of.docVIP

 PAGE \* MERGEFORMAT 4 Mesenchymal stem cell transplantation for treatment of nervous system diseases liver and kidney function in patients with short-term clinical observation of Author: Cao Hong Jian-Ping Zhu Jun Shi Tao Ma Huang Wei Xiu [Keywords:] mesenchymal stem cell transplantation for liver and kidney function in nervous system diseases Mesenchymal stem cells (Mesenchymal Stem Cells, MSCs) are adult stem cells, a kind of self-renewing, highly proliferative and multi-differentiation potential characteristics and a low immunogenic and immune conditioning [1 ~ 3] the characteristics of its applications are embryonic stem cells avoids the ethical issues brought about by [4], has gradually become cell therapy and gene therapy is an ideal target cell, in biology and tissue engineering has great scientific value. MSCs wide variety of sources, from different tissues of the human body can be isolated to a variety of subtypes of mesenchymal stem cells (MSCs), in which bone marrow-derived mesenchymal cells have been widely used in fields of study. A growing number of animal experiments and clinical studies have shown that human umbilical cord blood (Human Umbilical Cord Blood, HUCB) exist in a rich mesenchymal stem cells. In view of umbilical cord blood derived easily, sources rich in immune-derived weak, can tolerate a greater degree of HLA matching does not match the characteristics, the authors have umbilical cord blood MSCs as a ‘seed’ cells used to treat a variety of diseases, so that it from the blood system diseases is commonly used extended to a variety of diseases, research and treatment, and further extends the value of cord blood cells [5 ~ 7]. In order to promote and realize the value of these applications, it is necessary to understand the umbilical cord blood mesenchymal stem cells (Umbilical Cord Mesenchymal Stem Cells, UCMSCs) security. This author of Zhejiang Xiaoshan hospital treatment and rehabilitation centers UCMSCs cell transplant patient